Gastrointestinal Cancer Biology Laboratory
Our lab conducts translational research that focuses on GI malignancies. One primary focus of our lab is how cancers become resistant to chemotherapies. We are currently investigating colon and pancreatic cancer.
(in chronological order)
Debashish Bose, Eric Tamm, Jun Liu, Leonardo Marcal, Aparna Balachandran, Priya Bhosale, Jason B. Fleming, Jeffrey E. Lee, Douglas B. Evans, Rosa F. Hwang Multidisciplinary Management Strategy for Incidental Cystic Lesions of the Pancreas. Journal of the American College of Surgeons. 2010; 211: 205-215.
Bose D, Meric-Bernstam F, Hofstetter W, Reardon DA, Flaherty KT, Ellis LM. Vascular endothelial growth factor targeted therapy in the perioperative setting: implications for patient care. Lancet Oncol. 2010 Apr;11(4):373-82.
Debashish Bose, MD PhDGaur P, Bielenberg DR, Samuel S, Bose D, Zhou Y, Gray MJ, Dallas NA, Fan F, Xia L, Lu J, Ellis LM. Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis. Clin Cancer Res. 2009 Nov 15;15(22):6763-70
Puja Gaur, Debashish Bose, Shaija Samuel, and Lee M Ellis, Targeting Tumor Angiogenesis, Semin Oncol 36 (Suppl 1): S12-19, April 2009
Badgwell B, Cormier JN, Xing Y, Yao J, Bose D, Krishnan S, Pisters P, Feig B, Mansfield P. Attempted salvage resection for recurrent gastric or gastroesophageal cancer. Ann Surg Oncol. 2009 Jan; 16(1):42-50.
Samaniego F, Pati S, Karp JE, Prakash O, Bose D. Human herpesvirus 8 K1-associated nuclear factor-kappa B-dependent promoter activity: role in Kaposi's sarcoma inflammation? J Natl Cancer Inst Monogr. 2001;(28):15-23. Genbank submission: AF170531 for gene sequence.
Hunter JC, Smith CC, Bose D, Kulka M, Broderick R, Aurelian L. Intracellular internalization and signaling pathways triggered by the large subunit of HSV-2 ribonucleotide reductase (ICP10). Virology. 1995;210(2):345-60.
Bostwick DG, Srigley J, Grignon D, Maksem J, Humphrey P, van der Kwast TH, Bose D, Harrison J, Young RH. Atypical adenomatous hyperplasia of the prostate: morphologic criteria for its distinction from well-differentiated carcinoma. Hum Pathol. 1993;24(8):819-32.